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Herbal medicine adverse effect, plus 21 other Hurley publications first half of 2023

When one Flint-area resident used kratom - an herbal supplement derived from an evergreen tree in the coffee family and often consumed as tea, smoked, or chewed - he never expected it to cause difficulty breathing. But acute respiratory distress syndrome brought him to Hurley Medical Center, where his team of physicians figured out the problem fast enough to save his life, despite some challenges on his road to recovery.

That case was described by six resident physicians and faculty members at Hurley Medical Center, and it was published in the European Journal of Case Reports in Internal Medicine in March of 2023, with the lead author of Justine Chinnappan MD, a second-year Internal Medicine resident physician at the time. The conclusion: Physicians need to be aware of the increasing use of kratom and its various serious side effects.

That paper is just one example of the type of scholarly activity at Hurley Medical Center. See more details about it - and 21 others - below, with Hurley-affiliated authors in bold.

  1. Nageshwari Palanisamy, Justine Chinnappan, Ghassan Bachuwa. Pain Management Options in a Patient with Livedoid Vasculopathy and Peripheral Neuropathy. Eur J Case Rep Intern Med. 2023 Jan 30;10(1):003727. PMID: 36819654
  2. Justine Chinnappan, Murtaza Hussain, Dominic Awuah, Ekwevugbe Ogbon, Ghassan Bachuwa, Philip McDonald. Extraintestinal Clostridioides difficile Infection (CDI): A Recurrent Battle with Resilient Abdominal Wall Abscess. Eur J Case Rep Intern Med. 2023 Jan 5;10(1):003711. PMID: 36819648
  3. Alsayid M, Ahmad Taftaf, Harmouch KM, Alabkaa A, Pappas SG, Singh A. Sarcoidosis of the Bile Duct. ACG Case Rep J. 2023 Feb 1;10(1):e00964. 2023 Jan. PMID: 36743331
  4. Idolor O, Edigin E, Eseaton PO, Trang A, Kichloo A, Shaka H, Efosa Martins Bazuaye, Okobia NO, Eboma JE, Uwumiro F, Sandhu VK, Manadan A. Systemic lupus erythematous readmissions have reduced: a 9-year longitudinal study of the nationwide readmission database. Clin Rheumatol. 2023 Feb;42(2):377-383. PMID: 36534352
  5. Karna R, Smit Deliwala, Ramgopal B, Mohan BP, Kassab L, Becq A, Dhawan M, Adler DG. Efficacy of topical hemostatic agents in malignancy-related GI bleeding: a systematic review and meta-analysis. Gastrointest Endosc. 2023 Feb;97(2):202-208.e8. PMID: 35944608
  6. Cummings BC, Blackmer JM, Motyka JR, Farzaneh N, Cao L, Bisco EL, James D. Glassbrook, Michael D. Roebuck, Gillies CE, Admon AJ, Medlin RP Jr, Singh K, Sjoding MW, Ward KR, Ansari S. External Validation and Comparison of a General Ward Deterioration Index Between Diversely Different Health Systems. Crit Care Med. 2023 Mar 16. PMID: 36927631
  7. Justine Chinnappan, Abinash Parajuli, Huda Marcus, Ghassan Bachuwa. Constipation in transverse myelitis. BMJ Case Rep. 2023 Mar 6;16(3):e254409. PMID: 36878618
  8. Ramai D, Enofe I, Smit Deliwala, Mozell D, Facciorusso A, Gkolfakis P, Mohan BP, Chandan S, Previtera M, Maida M, Anderloni A, Adler DG, Ofosu A. Early (<4 weeks) versus standard (≥4 weeks) endoscopic drainage of pancreatic walled-off fluid collections: a systematic review and meta-analysis. Gastrointest Endosc. 2023 Mar;97(3):415-421.e5. PMID: 36395824!/content/journal/1-s2.0-S001651072202140X
  9. Edigin E, Trang A, Ojemolon PE, Eseaton PO, Shaka H, Kichloo A, Efosa Martins Bazuaye, Okobia NO, Okobia RI, Sandhu V, Manadan A. Longitudinal trends of systemic lupus erythematous hospitalizations in the United States: a two-decade population-based study. Clin Rheumatol. 2023 Mar;42(3):695-701. PMID: 36287285
  10. Mack D, Mohamed Hussein, Gul Sachwani-Daswani, Kristoffer Wong. Extraocular sebaceous carcinoma of the chest wall: A case report. Int J Surg Case Rep. 2023 Apr 13;106:108195. PMID: 37068454!...
  11. Jacob Nosewicz, Nash J. Resolution of post-zoster granulomatous dermatitis with valacyclovir. Int J Dermatol. 2023 Apr;62(4):e205-e207.
  12. Skolarus LE, Dinh M, Kidwell KM, Lin CC, Buis LR, Brown DL, Rockefeller Oteng, Giacalone M, Warden K, Trimble DE, Whitfield C, Farhan Z, Flood A, Dominic Borgialli, Montas S, Michael Jaggi, Meurer WJ.
    Reach Out Emergency Department: A Randomized Factorial Trial to Determine the Optimal Mobile Health Components to Reduce Blood Pressure. Circ Cardiovasc Qual Outcomes. 2023 May;16(5):e009606. PMID: 37192282 Clinical Trial. Full text available here:
  13. Rami Al-Handola, Justine Chinnappan, Murtaza Hussain, Abdullahi Mahgoub, Ghassan Bachuwa. Antimitochondrial Antibody-Negative Primary Biliary Cholangitis: A Retrospective Diagnosis.
    Cureus. 2023 Mar 17;15(3):e36309. PMID: 37073193. Full text available here:
  14. Mack D, Mohamed A. Hussein, Gul Sachwani-Daswani, Kristoffer Wong. Extraocular sebaceous carcinoma of the chest wall: A case report. Int J Surg Case Rep. 2023 May;106:108195. PMID: 37068454. Full text available here:!...
  15. Justine Chinnappan, Jesus Aguirre, Huda Marcus, Qazi Azher, Ghassan Bachuwa. A Fatal Case of Systemic Calciphylaxis in the Gastrointestinal Tract: A Case Report and Literature Review. Cureus. 2023 Mar 24;15(3):e36641. PMID: 37101995. Full text available here: https://pubmed.ncbi.nlm.nih.go...
  16. Justine Chinnappan,Yasaman Navari, Diane Casini, Nageshwari Palanisamy, Niraj Parikh, Elfateh Seedahmed. Kratom-Induced Acute Respiratory Distress Syndrome (ARDS). Eur J Case Rep Intern Med. 2023 Mar 29;10(4):003835. PMID: 37051477. Full text available here:
  17. Deepesh Yadav, Sailendra Shah, Ghassan Bachuwa. A Rare Presentation of Sarcoidosis: Dysphagia, Pancytopenia, and Acute Renal Failure. Cureus Journal of Medical Science 2022;14(6).
  18. Tessema ST, Abdullani E. Mahgoub, Nakhleh R. Angiosarcoma: A Rare Malignancy Linked to Chemical Exposures. Cureus. 2022 May 24;14(5):e25289. PMID: 35755516.
  19. Warring SK, Cope AG, Youssef Youssef, Burnett TL, Langstraat CL, Behm KT, Khan Z. Excision of Deep Endometriosis of the Rectosigmoid: Individualizing Care to the Presenting Pathology. J Minim Invasive Gynecol. 2022 Jun 22:S1553-4650(22)00255-2. PMID: 35752391!/content/journal/1-s2.0-S1553465022002552
  20. Ramai D, Smit Deliwala, Chandan S, Lester J, Singh J, Samanta J, di Nunzio S, Perversi F, Cappellini F, Shah A, Ghidini M, Sacco R, Facciorusso A, Giacomelli L. Risk of Hepatocellular Carcinoma in Patients with Porphyria: A Systematic Review. Cancers (Basel). 2022 Jun 15;14(12):2947. PMID: 35740611
  21. Akram Al-Salman, Dominic Awuah, Ann Sedeeq, Mohammed L Alkotob. Unmasking acute aortic root dissection in otherwise stable atypical chest pain. Clin Case Rep. 2022 Jun 13;10(6):e5962. PMID: 35734192
  22. Aisha Akhtar, Santosh Dhungana, Nidhi Bhagat, Ghassan Bachuwa. Left internal jugular vein thrombosis secondary to pacemaker insertion. PMID: 35662772

    Jennifer Godlesky of the Hurley Medical Library contributed to this blog.

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